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Research Blog

The latest in peptide science, research updates, and educational resources

Compounds

Retatrutide and the Case for a Third Receptor

Retatrutide adds glucagon receptor agonism to the GIP/GLP-1 pairing. That third arm changes the mechanism in a way worth understanding before you design around it.

Feb 4, 2026 · 6 min read
Compounds

Tirzepatide: What the GIP Arm Actually Contributes

Tirzepatide pairs GIP and GLP-1 receptor agonism. The GIP half is the part the literature still argues about — and the argument is more interesting than the consensus.

Feb 11, 2026 · 5 min read
Compounds

NAD+ and the Problem With Giving Cells the Molecule They Need

NAD+ sits at the centre of cellular energy metabolism and declines with age. Raising it is harder than it sounds, and the reason is a good lesson in bioavailability.

Feb 18, 2026 · 6 min read
Compounds

GHK-Cu: Why the Copper Is Not Optional

GHK-Cu is a three-amino-acid peptide bound to a copper ion. The peptide alone behaves differently from the complex, and that distinction runs through the whole literature.

Feb 25, 2026 · 5 min read
Compounds

MOTS-c: A Peptide the Mitochondria Wrote

MOTS-c is encoded in mitochondrial DNA, not nuclear DNA. That origin is not trivia — it reframes what mitochondria are understood to do.

Mar 4, 2026 · 6 min read
Compounds

Tesamorelin: Stimulating a Pathway Rather Than Replacing It

Tesamorelin is a GHRH analog. It prompts the pituitary to release growth hormone rather than supplying growth hormone directly, and that difference has real consequences.

Mar 11, 2026 · 5 min read
Guides

Reconstitution, Step by Step — and the Mistakes That Cost You a Vial

Reconstitution is simple to do and easy to do badly. The common errors are mechanical, not chemical, and every one of them is avoidable.

Mar 18, 2026 · 6 min read
Guides

Storage and Handling: What Actually Degrades a Peptide

Four things degrade peptides — temperature, moisture, light and freeze-thaw cycling. Understanding which one you are fighting tells you what to do about it.

Mar 25, 2026 · 5 min read